Role of Platelet Function Test in Predicting Postoperative Bleeding Risk after Coronary Artery Bypass Grafting: A Prospective Observational Study

Abstract Patients undergoing cardiac surgery are at risk of excessive bleeding and its associated complications. Excessive during after has an incidence ~20%. Massive subsequent requirement for blood product administration mediastinal reexploration with significant morbidity mortality. Postoperative, nonsurgical in surgical patients is often multifactorial. Platelet dysfunction, fibrinolysis, hypothermia, preoperative anemia, deficiency coagulation factors or their dilution all suggested etiologies postoperative bleeding. In the Arachidonic Acid Thromboelastometry (ARATEM) test, platelets activated arachidonic acid; Adenosine diphosphate (ADPTEM) adenosine diphosphate; TRAPTEM thrombin receptor-activating peptide 6. Measurement time 6 minutes, results expressed three different parameters: A6 (amplitude Ohm); MS (maximum slope aggregation curve Ohm/min), AUC (area under Ohm.min). Algorithm-based point-of-care platelet function testing helped us to preemptively give right component therapy, avoiding fibrinolytic period.